Dwars door Vlaanderen will go ahead on Wednesday, despite the terrorist attacks that hit Brussels on Tuesday, but Giant-Alpecin will not be on the start line.
The German-registered team was left with just two riders who could make it to Belgium on time after all flights to the capital were cancelled.
>> Subscribe to Cycling Weekly this Autumn and save 35%. Enjoy the luxury of home delivery and never miss an issue <<
Chad Haga, who was set to make his comeback from injuries suffered in a training crash in January, was held up in Spain with Caleb Fairly, while Frederik Ludvigsson was stuck in Sweden.
Due to the injuries suffered in a collision with a car in Calpe the team was already down to the minimum of six riders, rather than the allowed eight.
Movistar are reportedly badly hit as well; set to start the race with just four riders after Antonio Pedrero, Nelson Oliveira, Carlos Betancur and Jorge Arcas were removed from the line-up.