Having seen a record number of starters remain until the first rest day at the Tour de France in July, a tough route and some tired bodies has seen a huge number of retirements from the Vuelta a España.
There have been crashes a plenty, including two for Astana leader Miguel Angel Lopez, who continued after losing a few teeth only to crash again and have to abandon the race.
Simon Clarke of Cannondale-Drapac also hit the tarmac, fracturing his shoulder in a crash on stage 10, although he did make it to the finish, only to discover the full extent of his injuries.
Here is the full list of abandonments ahead of stage 13 of the race.
Nathan Haas (Dimension Data)
Florian Sénéchal (Cofidis)
Fabrice Jeandesboz (Direct Energie)
Silvio Herklotz (Bora-Argon 18)
Simon Clarke (Cannondale-Drapac)
Patrick Bevin (Cannondale-Drapac)
Jose Goncalves (Caja Rural)
Bartosz Huzarski (Bora-Argon 18)
Markel Irizar (Trek-Segafredo)
Kevin Reza (FDJ)
Igor Anton (Dimension Data)
Yoann Bagot (Cofidis)
Tony Hurel (Direct Energie)
Enrico Battaglin (LottoNL-Jumbo)
Rein Taaramae (Katusha)
Niccolo Bonifazio (Trek-Segafredo)
Michal Kwiatkowski (Team Sky)
Miguel Angel Lopez (Astana)
Sebastian Minard (Ag2r La Mondiale)
Robert Kiserlovski (Tinkoff)Steven Kruijswijk (LottoNL-Jumbo)
Lluis Mas (Caja Rural-Seguros RGA)
Murilo Fischer (FDJ)
Federico Zurlo (Lampre-Merida)
Vicente Reynes (IAM Cycling)
Warren Barguil (Giant-Alpecin)