The Giant-Alpecin man has made no secret of his desire to win the long 40.5km Chianti time trial on stage nine, despite playing down his GC chances, and could jump right back into the frame if he does it.
But who will be the biggest losers? The likes of Esteban Chaves (Orica-GreenEdge) and Mikel Landa (Team Sky) as far from known for their time trial prowess, and will be looking to still be within touching distance as the race heads into a rest day on Monday.
The likes of Alejandro Valverde (Movistar) and Vincenzo Nibali (Astana) have proven their ability against the clock in the past, and could see their situations improve ahead of some tough mountain stages in week two of the race.
Ahead of the crucial time trial, we asked around the Giro d’Italia who would come off best after the stage and how the riders would approach the course.